The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Cellular Classification

Added text about levels of evidence, used to help readers judge the strength of evidence linked to reported results.

Added text about translocation-positive carcinomas, a distinct form of RCC, and their related genetic factors (cited Geller et al. and Camparo et al. as references 34 and 35, respectively).

Added text to state that recurrence of MCN has been reported following tumor spillage at surgery (cited Baker et al. as reference 44 and level of evidence 3iiiA).

Added Anaplastic Sarcoma of the Kidney as a new subsection.

Clear Cell Sarcoma of the Kidney

Added text about levels of evidence, used to help readers judge the strength of evidence linked to reported results.

Added text to state that recurrence of CCSK in the brain has been successfully treated with combination chemotherapy, surgery, and radiation therapy (cited Radulescu et al. as reference 4 and added level of evidence 2A).

Recurrent Wilms Tumor and Other Childhood Kidney Tumors

Added text about levels of evidence, used to help readers judge the strength of evidence linked to reported results.

Added level of evidence 2A for Malogolowkin et al. (reference 2).

Added text to state that in NWTS-5, patients with CCSK and brain metastases have been successfully treated with combination chemotherapy, surgery, and radiation therapy (cited Seibel et al. as reference 12).

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